Health Desk- 16 Feb, 2020: A single dose of human
papillomavirus (HPV) vaccine is associated with a significant reduction in
cervical disease, according to a retrospective study in Cancer.
The CDC generally recommends two doses for those vaccinated
between ages 9 and 14, and three doses for those vaccinated later.
Using a U.S. insurance claims database, researchers matched
nearly 67,000 females aged 9 to 26 who received at least one dose of the
quadrivalent HPV vaccine with 67,000 unvaccinated controls.
The estimated rate of preinvasive cervical disease at 5
years was 2.65% in the unvaccinated group, versus 1.62%, 1.99%, and 1.86% among
those who received one, two, and three vaccine doses, respectively, between
ages 15 and 19. After multivariable adjustment, one vaccine dose was associated
with a 36% risk reduction; two doses, a 28% reduction; and three doses, a 34%
reduction.
http://amarhealth.com/pharmaceuticals/4725/SingleHPVvaccinemayhelppreventcervicaldisease
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